Publications*
(for research performed @BLL since 1996)
This website may contain copyrighted material whose use, including
reproduction, is governed by
Peer-reviewed Publications
1.
A.
Lembares, X.H. Hu, G.W. Kalmus,
"Absorption
spectra of the cornea in the far ultraviolet region", Investigative
Ophthalmology & Visual Science, 38, 1283-1287 (1997)
2.
R.
Fu, G. Wang, Z. Wang, E. Ba, G. Mu, X.H. Hu, "Design of efficient lens ducts", Applied
Optics, 37, 4000-4003 (1998)
3.
Z.
Song, K. Dong, X. H. Hu, and J. Q. Lu, "Monte Carlo simulation of converging Laser beams
propagating in biological tissues", Applied Optics, 38,
2944-2949 (1999)
4.
Jun
Q. Lu, Xin-Hua Hu, Ke Dong, "Light
distribution of a converging laser beam in a two-layer skin model with rough
interfaces", Applied Optics, 39, 5890-5897
(2000)
5.
Y.
Du, X.H. Hu, M. Cariveau, X.Ma,
G.W. Kalmus, J. Q. Lu, "Optical properties of porcine skin dermis between 900nm
and 1500 nm", Physics in Medicine and Biology, 46,
167-181 (2001)
6.
X.H.
Hu, Q. Fang, M. Cariveau, X. Pan, G.W. Kalmus, "Mechanism study of porcine skin ablation by nanosecond
laser pulses at 1064, 532, 266 and 213 nm", IEEE
Journal of Quantum Electronics, 37, 322-328 (2001)
7.
X.H.
Hu, W. A. Wooden, S.J. Vore, M. Cariveau,
Q. Fang, G.W. Kalmus, “In vivo study of intradermal
focusing for tattoo removal”, Lasers in Medical Science, 17,
154-164 (2002)
8.
X.
Ma, J.Q. Lu, X.H. Hu, “Effect of surface roughness on determination of bulk
tissue optical parameters”, Optics Letters , 28,
2204-2206 (2003)
9.
X.
Ma, J.Q. Lu, R. S. Brock, K.M. Jacobs, P. Yang, X.H. Hu, “Determination of complex refractive index of polystyrene
microspheres from 370 to 1610 nm”, Physics in Medicine and Biology, 48, 4165-4172 (2003)
10. Q. Fang, X.H. Hu, “Modeling
of skin tissue ablation by Nanosecond pulses from ultraviolet to near-infrared
and comparison with experimental Results", IEEE
Journal of Quantum Electronics, 40, 69-77 (2004)
11. R.R. Allison, G.H.
Downie, R.E. Cuenca, X.H. Hu, C.J.H. Childs, C.H. Sibata, “Photosensitizers in clinical PDT”, Photodiagnosis and Photodynamic Therapy, 1,
27-42 (2004)
12.
P.
Yang, G. W. Kattawar, K.N. Liou,
J. Q. Lu, “Comparison of Cartesian grid configurations for
application of the finite-difference time domain method to electromagnetic
scattering by dielectric particles”, Applied Optics, 43, 4611-4624 (2004)
13.
R.R.
Allison, C. Sibata, T.S. Mang, V.S. Bagnato, G.H. Downie, X.H. Hu, R. Cuenca, “Photodynamic therapy for chest wall recurrence from
breast cancer”,
Photodiagnosis and Photodynamic Therapy, 1,
157-171 (2004)
14. X. Ma, J.Q. Lu, H.
Ding, X.H. Hu, “Bulk optical parameters of porcine skin dermis tissues at
8 wavelengths from 325 to 1557 nm”, Optics
Letters, 30, 412-414 (2005)
15.
J.Q. Lu, P. Yang, X.H. Hu, “Simulations of Light scattering from a biconcave red
blood cell using the FDTD method”, Journal of
Biomedical Optics, 10,
024022 (2005)
16. Y. Feng, R.R.
Allison, X.H. Hu, H. Mota, T. Jenkins, M.L.
Wolfe, C.H. Sibata, "An ultrasonic device for source to skin surface distance
measurement in patient setup", International
Journal of Radiation Oncology, Biology,
Physics, 61, 1587-1589 (2005)
17. H. Ding, J.Q. Lu,
K.M. Jacobs, X.H. Hu, "Determination of refractive Indices of porcine skin
tissues and intralipid at 8 wavelengths between 325
and 1557 nm",
Journal of the Optical Society of America A, 22, 1151-1157 (2005)
18. R. S. Brock, X.H. Hu,
P. Yang, J.Q. Lu, “Evaluation of a parallel FDTD code and application to
modeling of light scattering by deformed red blood cells”, Optics Express, 13, 5279-5292 (2005)
19. X.H. Hu, Y. Feng,
J.Q. Lu, R.R. Allison, R.E. Cuenca, G.H. Downie, C.H. Sibata, “Modeling of a
type II Photofrin-Mediated photodynamic therapy process in a heterogeneous
tissue phantom”,
Photochemistry and Photobiology , 81,
1460-1468 (2005)
20. H. Ding, J.Q. Lu,
W.A. Wooden, P.J. Kragel, X.H. Hu, “Refractive
indices of human skin tissues at eight wavelengths and estimated dispersion
relations between 300 and 1600 nm”, Physics in Medicine and Biology, 51,
1479-1489 (2006)
21. R. S. Brock, X.H. Hu, D.A. Weidner, J.R. Mourant, J.Q. Lu, "Effect of detailed cell structure on light scattering distribution: FDTD study of a B-cell with 3D structure constructed from confocal images", Journal of Quantitative Spectroscopy & Radiative Transfer, 102, 25-36 (2006)
22. C. Chen, J.Q. Lu, H.
Ding, K.M. Jacobs, Y. Du, X.H. Hu, “A primary method for determination of optical parameters
of turbid samples and application to intralipid
between 550 and 1630 nm”, Optics
Express, 14,
7420-7435 (2006)
23. W. Tang, D.A.
Weidner, B.Y. Hu, R.J. Newton, X.H. Hu, “Efficient delivery of small interfering RNA to plant
cells by a nanosecond pulsed laser-induced stress wave for posttranscriptional
gene silencing”, Plant Science,
171, 375-381 (2006)
24. H. Ding, J.Q. Lu, R.S. Brock, T.J. McConnell, J.F. Ojeda, K.M. Jacobs, X.H. Hu, “Angle-resolved Mueller matrix study of light scattering by B-cells at three wavelengths of 442, 633 and 850 nm”, Journal of Biomedical Optics, 12, 034032 (2007)
25. C. Chen, J.Q. Lu, K. Li, S. Zhao, R.S. Brock, X.H. Hu, “Numerical
study of reflectance imaging using a parallel Monte Carlo method”, Medical Physics, 34,
2939-2948 (2007)
26. M.A. Yurkin, A.G. Hoekstra, R.S. Brock, J.Q.
Lu, “Systematic comparison of the discrete dipole
approximation and the finite difference time domain method for large dielectric
scatterers”, Optics
Express, 15,
17902-17911 (2007)
27. J.Q. Lu, C. Chen,
D.W. Pravica, R.S. Brock, X.H. Hu, “Validity of a closed-form diffusion solution in P1
approximation for reflectance imaging with an oblique beam of arbitrary profile”, Medical Physics, 35, 3979-3987 (2008)
28.
Z. Yuan, X.H.
Hu, H. Jiang, “A higher order diffusion model for three-dimensional
photon migration and image reconstruction in optical tomography”, Physics in Medicine and
Biology, 54,
67-90 (2009)
29.
(invited) K.M. Jacobs, L.V. Yang, J. Ding, A.E. Ekpenyong, R.
Castellone, J.Q. Lu, X.H. Hu, “Diffraction imaging of spheres and melanoma cells with a
microscope objective”, Journal of
Biophotonics, 2, 521–527 (2009)
30. K.M. Jacobs, J.Q. Lu, X.H. Hu, “Development of a diffraction imaging flow cytometer”, Optics
Letters, 34, 2985-2987 (2009)
Invited
Review Articles and Book Chapters
1. J.Q. Lu, X.H. Hu ,
"Modeling of Light Scattering in Biological Systems",
invited article in Recent Research Developments in Optics, vol. 2, 541-563 (Research Signpost, 2002)
1. X.H. Hu, J.Q. Lu, “Optical detection of cancers”, in Encyclopedia of Biomaterials and Biomedical Engineering, ed. by
G.E. Wnek and G.L. Bowlin
(Marcel Dekker, 2005)
2. X.H. Hu, W. Tang, K.
Li, J.Q. Lu, “Transgenic plants with efficient laser-mediated gene
transformation and multispectral imaging based rapid monitoring”, in Genes, Genomes and Genomics, vol. 1, ed. by D. Thangadurai, W. Tang and T. Pullaiah
(Regency Publications, 2006)
3. J.Q. Lu, R. S. Brock,
P. Yang, X.H. Hu, "Modeling of light scattering by single red blood cells
with a FDTD method", in Optics of Biological Particles, ed. by A.
Hoekstra, G. Videen and V. Maltsev
(Springer, 2007)
Proceeding
Publications and Conference Presentations
1.
X.H.
Hu, A. Lembares, G.W. Kalmus,
"Surface ablation of porcine skin tissue using nanosecond laser pulses at
1064 nm", SPIE Proceedings, 2970, 335-337 (1997)
2.
Lembares, X.H. Hu, G.W. Kalmus,
"Far ultraviolet absorption spectra of porcine and human corneas", SPIE
Proceedings, 2971, 46-54 (1997)
3.
K.
Dong, Z. Song, J. Q. Lu, X.H. Hu, "Monte Carlo Simulation of Converging
Laser Beams Propagating in Skin Tissue Phantoms", SPIE Proceedings,
3590, 4-10 (1999)
4.
J.
Q. Lu, X.H. Hu, Z. Song, K. Dong, "Simulation of light scattering in
biological tissues: the coherent component", SPIE Proceedings, 3601,
474-481 (1999)
5.
Y.
Du, M. Cariveau, G.W. Kalmus,
J. Q. Lu, X.H. Hu, "Experimental Study of Optical Properties of Porcine
Skin Dermis from 900 to 1500nm", SPIE Proceedings, 3917,
184-192 (2000)
6.
X.H.
Hu, Q. Fang, M. Cariveau, X. Pan, G.W. Kalmus, "Ablation of Skin Tissue by Nanosecond Laser
Pulses at 1064, 532, 266 and 213nm", SPIE Proceedings, 3914,
110-115 (2000)
7.
D.
Wu, S. S. Zhao, J. Q. Lu, X. H. Hu, "Monte Carlo Simulation of Light
Propagation in Skin Tissue Phantoms Using a Parallel Computing Method", SPIE
Proceedings, 3914, 291-299 (2000)
8.
J.
Q. Lu, K. Dong, X. H. Hu, "Effects of Rough Interfaces on a Converging
Laser Beam Propagating in a Skin Tissue Phantom", SPIE Proceedings,
3917, 176-183 (2000)
9.
X.H.
Hu, W. A. Wooden, M.J. Cariveau, Q. Fang, J.F.
Bradfield, G.W. Kalmus, S.J. Vore,
Y. Sun, "Tattoo removal in micropigs with low-energy
pulses from a Q-switched Nd:YAG laser at
1064nm", SPIE Proceeding, 4244, 55-60 (2001)
10.
J.Q.
Lu, P. Yang, X.H. Hu, “Accurate Simulation of Light Scattering by a Red Blood
Cell using the FDTD Method”, CLEO 2002, paper CThO65
11.
Q.
Fang and X.H. Hu, “Quantitative Understanding of Skin Tissue Ablation from UV
to NIR with a New Plasma Model”, CLEO 2002, paper CWJ17
12. X. Ma, J.Q. Lu, X.H.
Hu, “Measuring the Bulk Optical Properties of Skin Tissue Samples with Rough
Surfaces”, OSA Annual Meeting 2002, paper WQ1
13. H. Ding, K.M. Jacobs,
X.H. Hu, “Refractive Index of Skin Tissues from 325 to 1550nm”, OSA Annual
Meeting 2002, paper WQ2
14. D. Pravica, J.Q. Lu,
X.H. Hu, “The Limits of Light Diffusion Approximation”, OSA Annual Meeting
2002, paper WQ3
15. J.Q. Lu, X.H. Hu,
“Understanding of Flow Cytometry using FDTD Simulations”, OSA Annual Meeting
2002, paper WQ4
16. J.Q. Lu, C.H. Sibata,
R. S. Brock, R. R. Allison, G. H. Downie, R. E. Cuenca, X.H. Hu, “Optimization
of PDT Treatment with Multiple Laser Beams Using a Parallel Monte Carlo Code”,
AAPM Annual Meeting 2003, San Diego, California (abstract: Medical Physics,
30, 1513 (2003))
17. X.H. Hu, J.Q. Lu, R.
R. Allison, G. H. Downie, R. E. Cuenca, C.H. Sibata -Monte Carlo Based Model of
Photodynamic Therapy Process”, AAPM Annual Meeting 2003, San Diego, California
(abstract: Medical Physics, 30, 1513 (2003))
18. X.H. Hu, Y.
Feng, R.E. Cuenca, J. Q. Lu, K.M. Jacobs, Y. Ti, C.H. Sibata, “In Vivo Polarimetric Spectral Imaging
and Multivariate Analysis of Dysplastic Lesions”, Optical Imaging Workshop
2004: Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench
to Bedside at the National Institutes of Health, NIH04-NIH101-225
19. Y. Feng, R. Cuenca,
K.M. Jacobs, Y. Ti, J.Q. Lu, S. Jackson, P. Gemperline, R. Allison, C.H.
Sibata, G. Downie, X.H. Hu, “In Vivo multispectral imaging for diagnosis of
melanoma”, OSA Annual Meeting 2004, paper FTuL5
20. X. Ma, J.Q. Lu, X.H.
Hu, “In Vitro determination of bulk tissue optical parameters of porcine skin
dermis”, OSA Annual Meeting 2004, paper FTuG51
21. R.S. Brock, X.H. Hu,
D. Weidner, Y. Feng, “Modeling of light scattering by B-cells using a parallel
FDTD method”, OSA Annual Meeting 2004, paper FTuG49
22. J.Q. Lu, Y. Feng,
R.E. Cuenca, Y. Ti, K. Li, K.M. Jacobs, S.B. Jackson, R.R. Allison, C.H.
Sibata, G.H. Downie, X.H. Hu, “Multivariate Analysis of Monte Carlo Generated
Images for Diagnosis of Dysplastic Lesions”, SPIE Proceedings, 5692, 29-36 (2005)
23. R.S. Brock, X.H. Hu,
P. Yang, J.Q. Lu, “Simulation of light scattering by a pressure deformed red
blood cell with a parallel FDTD method" SPIE Proceedings, 5702, 69-75 (2005)
24. K. Li, J.Q. Lu, R.S.
Brock, B. Yang, X.H. Hu, “Quantitative Modeling of Skin Images Using Parallel
Monte Carlo Methods", SPIE Proceedings, 5693, 82-87 (2005)
25. X. Ma, H. Ding, J.Q.
Lu, K.M. Jacobs, Y. Sun, X.H. Hu, “Bulk Tissue Optical Parameters of Porcine
Skin Dermis at 8 Wavelengths from 325 to 1550nm", SPIE Proceedings,
5695, 75-82 (2005)
26.
G. Downie, Y.Y. Huang, X.H. Hu, C. Sibata, R.
Allison, R. Cuenca, C. Childs,
“Tumor ablation through self-expandable metal stent
(SEMS) for airway neoplasm: The dosimetry and efficacy of photodynamic
therapy”, 11th World Conference on Lung Cancer (IASLC), July,
2005, Barcelona, Spain. (Abstract Number: 946.00)
27. J. Q. Lu, C. Chen, K.
Li, K. M. Jacobs, B. Yang, X.H. Hu, “Imaging
Based Tissue Optics: Parallel Monte Carlo Modeling and Phantom Measurements”, OSA
Annual Meeting 2005, paper JWA47
28. R.S. Brock, X.H. Hu,
H. Ding, J.Q. Lu, D.A. Weidner, “Parallel
FDTD Simulation of Light Scattering by Three-Dimensional B Cells at Different
Phases of Cell Cycle”, OSA Annual Meeting 2005, paper JWA45
29. J.Q. Lu, R.S. Brock, X.H. Hu, P. Yang, D.A. Weidner, “Numerical simulations
of light scattering from blood cells using FDTD method”, NATO Advanced
Research Workshop on Optics of Biological Particles, October 3-6, 2005,
Novosibirsk, Russia
30. R.S. Brock, X.H. Hu,
D.A. Weidner, J.R. Mourant, J.Q. Lu, “3D Reconstruction of B-lymphocytes with
Confocal Images and Parallel FDTD Simulations of Light Scattering”, OSA Biomedical
Optics Topical
Meeting,
paper MC8, March 19-22, 2006, Miami, Florida
31. H. Ding, J.Q. Lu, R.S. Brock, D.A. Weidner, T.J. McConnell, L.P. Burke, X.H. Hu, “Angle-resolved Mueller Matrix Study of Light Scattering by B-Cells and HL-60 Cells at Three Wavelengths of 442, 633 and 850nm”, OSA Biomedical Optics Topical Meeting, paper ME73, March 19-22, 2006, Miami, Florida
32. C. Chen, R.S. Brock,
D.W. Pravica, X.H. Hu, J.Q. Lu, “Fast Modeling of
Reflectance Image of Turbid Medium with Full-field Illumination”, Progress in Electromagnetics Research Symposium (PIERS 2006), March
26-29, 2006, Cambridge, MA
33. H.
Ding, J.Q. Lu, C. Chen, G.E.
Downie, X.H. Hu, “Determination of Local Optical Parameters of Turbid
Media with Optical Fibers”, OSA Annual Meeting 2006,
paper JWD56
34. H.
Ding, J.Q. Lu, R. S. Brock, L.P.
Burke, D.A. Weidner, T.J. McConnell, X.H.
Hu, “Determination of Intracellular Distributions of Refractive Index of
B-cells and HL60 cells at 442, 633 and 850nm”, OSA
Annual Meeting 2006, paper FTuQ1
35. R.S.
Brock, H. Ding, D.A. Weidner, T.J.
McConnell, X.H. Hu, J.R. Mourant, J.Q. Lu, “Modeling of the Internal Optical Structure of the
Nuclei of B-cells”, OSA Annual Meeting
2006, paper FTuE2
36. H. Ding, J.Q. Lu, R.S. Brock, L. P. Burke, D. A. Weidner, T. J. McConnell, X.H. Hu, “Angle-resolved Measurement and Simulations of Mueller Matrix of B-cells
and HL60 cells”, Progress in Electromagnetics Research Symposium (PIERS 2007 in Beijing),
March 26-30, 2007, Beijing, China
37. C. Chen, K. M. Jacobs, J.Q. Lu, R. E. Cuenca, J. Finley, X.H. Hu, “In Vivo Measurement and Modeling of Multispectral Reflectance Images for
Melanoma Diagnosis”, Progress in Electromagnetics Research Symposium (PIERS 2007 in Beijing),
March 26-30, 2007, Beijing, China
38. H. Ding; J.Q. Lu,
R.S. Brock, L.B. Burke, D.A. Weidner, T.J. McConnell, X.H. Hu, “Experimental
Study of Angle-Resolved Mueller Matrix of B-cells and HL60 cells at 442, 633
and 850nm”, International Conference on
Laser Applications in Life Sciences 2007, Paper # 163, 11-14 June 2007,
Moscow, Russia
39. R.S.
Brock, X.H. Hu, D.A. Weidner, J.R.
Mourant, J.Q. Lu, “Simulations
of Light Scattering from B-cells with Inhomogeneous Nuclei
Using an Improved FDTD Program”, OSA
Biomedical Optics Topical Meeting, paper BTuF13, March 16-19, 2008,
St. Petersburg , Florida
40. C. Chen, J.Q. Lu, K. M. Jacobs, X.H. Hu, “Noninvasive
Determination of Optical Parameters from One Reflectance Image and Extension to
Depth-Resolving”, OSA Biomedical Optics Topical Meeting, paper
BTuF26, March 16-19, 2008, St.
Petersburg , Florida
41. J. Q. Lu, J. Ding, K.M. Jacobs, X.H. Hu,
“Diffraction Imaging of Biological Cells in Microfluidic Flow”, International Conference
on Laser Applications in Life Science (LALS) 2008, Paper Sat-S34-04
(invited), December 4-6, 2008, Taipei, Taiwan, Republic of China
42. A.E. Ekpenyong, J.
Ding, L.V. Yang, N.R. Leffler, J.Q. Lu, R.S. Brock, X.H. Hu, “Study of 3-D Cell Morphology and Effect on
Light Scattering Distribution”, Paper MJ58, European Conferences on
Biomedical Optics (ECBO), June 14-18, 2009, Munich, Germany
News Reports
1.
"Shinning light on cells", Biomedical Computation Review, Summer, 2005
2.
“Optical imaging of cells and
tissues”, Materials & Processes for Medical Devices/ ASM
International, April, 2009